Diethyl (4-iodobenzyl)phosphonate CAS 173443-43-1
| CAS No. | 173443-43-1 |
| Molecular Formula | C11H16IO3P |
| Molecular Weight | 354.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Diethyl (4-iodobenzyl)phosphonate (CAS 173443-43-1) is a high-purity analytical reference standard with the molecular formula C11H16IO3P and a molecular weight of 354.12 g/mol.
Diethyl (4-iodobenzyl)phosphonate (C11H16IO3P) contains a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H16IO3P |
| Molecular Weight | 354.12 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2006 |
| Halogen Content | I-containing |
Related Diethyl Standards
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- Diethyl 2-(5-ethoxycarbonyl-3-nitro-2-pyridyl)propanedioate (CAS 1630906-48-7)
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- 1,3-Diethyl 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methylpropanedioate (CAS 400075-21-0)
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Recommended Standards
- 6-Fluoro-2-(3-iodophenyl)-2H-benzo[d][1,2,3]triazol-5-amine (CAS 1706437-37-7)
- 1H,1H-Perfluorohexyl acrylate (CAS 376-56-7)
- 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-d]pyrimidine (CAS 1446712-64-6)
- 5,5,6,6,7,7,8,8,9,9,9-Undecafluorononane-2,4-dione (CAS 75824-01-0)
- (R)-3-(4-fluorophenyl)pyrrolidine (CAS 1048703-18-9)
- tert-Butyl 4-hydroxy-3,5-dimethylpiperidine-1-carboxylate (CAS 1420876-48-7)
- 2,6-Dioxo-3,6-dihydro-2H-pyran-4-yl acetate (CAS 15997-62-3)
- 4-Bromo-2-cyano-5-(difluoromethyl)pyridine-3-carbonyl chloride (CAS 1806057-11-3)
- 3,3,3-Trifluoro-2-(trifluoromethyl)propanoic anhydride (CAS 13049-92-8)
- Piperidin-2-yl(thiomorpholino)methanone (CAS 1218531-53-3)
- 3-(3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-yl)acrylic acid (CAS 773132-14-2)
- 2-tert-Butyl-1-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 113975-30-7)
- 2-Fluoro-5-(trifluoromethyl)isonicotinic acid (CAS 1227574-99-3)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
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