(R)-2-(3-chloro-5-(difluoromethyl)-4-fluorophenyl)pyrrolidine CAS 1446912-25-9
| CAS No. | 1446912-25-9 |
| Molecular Formula | C11H11ClF3N |
| Molecular Weight | 249.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (R)-2-(3-chloro-5-(difluoromethyl)-4-fluorophenyl)pyrrolidine (CAS 1446912-25-9), a certified reference material (molecular formula C11H11ClF3N, MW 249.66 g/mol) for analytical method development and quality control.
Structurally, (R)-2-(3-chloro-5-(difluoromethyl)-4-fluorophenyl)pyrrolidine (C11H11ClF3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 249.66 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), (R)-2-(3-chloro-5-(difluoromethyl)-4-fluorophenyl)pyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11ClF3N |
| Molecular Weight | 249.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 2-Chloro-N6-furfuryladenine (CAS 101862-47-9)
- (R)-2-(2-chloro-3-(trifluoromethyl)phenyl)pyrrolidine (CAS 1212902-02-7)
- (R)-2-(2-chloro-5-(trifluoromethyl)phenyl)pyrrolidine (CAS 1212917-82-2)
- (S)-2-(3-chloro-5-(trifluoromethyl)phenyl)pyrrolidine (CAS 1212943-00-4)
- (R)-2-(3-chloro-4-(trifluoromethyl)phenyl)pyrrolidine (CAS 1213504-17-6)
- (R)-2-(3-chloro-5-(trifluoromethyl)phenyl)pyrrolidine (CAS 1213630-65-9)
- (S)-(3-chloro-4-(trifluoromethyl)phenyl)(cyclopropyl)methanamine (CAS 1213642-16-0)
- (S)-2-(3-chloro-4-(trifluoromethyl)phenyl)pyrrolidine (CAS 1213673-37-0)
Recommended Standards
- 7-Chloro-6-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1337373-28-0)
- (S)-2-(3-chloro-5-(difluoromethyl)-4-fluorophenyl)pyrrolidine (CAS 1447055-22-2)
- (2-(4-Chloro-3-(trifluoromethyl)phenyl)cyclopropyl)methanamine (CAS 1315348-40-3)
- (R)-2-(4-chloro-3-(difluoromethyl)-2-fluorophenyl)pyrrolidine (CAS 1447108-01-1)
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