Ketorolac Impurity 42 CAS 144710-35-0
| CAS No. | 144710-35-0 |
| Molecular Formula | C18H19NO5 |
| Molecular Weight | 329.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Ketorolac Impurity 42 (CAS 144710-35-0, C18H19NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Ketorolac Impurity 42 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 329.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H19NO5 |
| Molecular Weight | 329.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 1 |
Related Ketorolac Standards
- Ketorolac Impurity 78 (CAS CATO-C4X-166978)
- Ketorolac Impurity 79 (CAS CATO-C4X-166979)
- Ketorolac 2-Benzoylpyrrole Iodo Impurity (CAS 141031-77-8)
- Ketorolac Impurity 29 (CAS CATO-C4X-166929)
- Ketorolac impurity 67 (CAS CATO-C4X-166967)
- Ketorolac Impurity 76 (CAS CATO-C4X-166976)
- Ketorolac impurity 70 (CAS CATO-C4X-166970)
- Ketorolac Impurity 37 (CAS CATO-C4X-166937)
Recommended Standards
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- Flumazenil Impurity 18 (CAS CATO-C4X-143218)
- Tetrabenazine Impurity 49 (CAS CATO-C4X-274849)
- Ioversol Impurity 6 (CAS 2922747-40-6)
- Furfural impurity 6 (CAS CATO-C4X-24886)
- (6-Methoxybenzofuran-2-yl)(4-methoxyphenyl)methanone (CAS 75158-60-0)
- 3-Nitro-5-(m-tolyloxy)aniline (CAS 352637-09-3)
- 4-Bromo-2,3-dimethylaniline (CAS 22364-25-6)
- 2,3-Dihydroxy-7,8,9,10-tetrahydro-6H-benzo[c]-chromen-6-one (CAS 197965-28-9)
- 6-(4-Formylpiperazin-1-yl)-4-methylnicotinic acid (CAS 1355229-26-3)
- 1-(4-Butoxyphenyl)-3-(4-(dimethylamino)phenyl)thiourea (CAS 500-89-0)
- Semaglutide impurity 48 (CAS CATO-C4X-222648)
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