1-((4-Chlorophenyl)sulfonyl)-4-(phenylsulfonyl)piperidine CAS 1448056-66-3
| CAS No. | 1448056-66-3 |
| Molecular Formula | C17H18ClNO4S2 |
| Molecular Weight | 399.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 399.91 g/mol gives 1-((4-Chlorophenyl)sulfonyl)-4-(phenylsulfonyl)piperidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-((4-Chlorophenyl)sulfonyl)-4-(phenylsulfonyl)piperidine (CAS 1448056-66-3), molecular formula C17H18ClNO4S2 and molecular weight 399.91 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-((4-Chlorophenyl)sulfonyl)-4-(phenylsulfonyl)piperidine (C17H18ClNO4S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-((4-Chlorophenyl)sulfonyl)-4-(phenylsulfonyl)piperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H18ClNO4S2 |
| Molecular Weight | 399.91 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 4-[2-(4-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl]-N-(4-methyl-1,3-thiazol-2-yl)pyrimidin-2-amine (CAS 1881329-72-1)
- 1-(4-Chlorophenyl)-3-(5-((2-morpholinoethyl)thio)-1,3,4-thiadiazol-2-yl)urea (CAS 922698-03-1)
- 2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamide (CAS 202591-23-9)
- 4-(4-Chlorophenyl)-2-phenyl-6-(phenylsulfanyl)pyrimidine-5-carbonitrile (CAS 320418-48-2)
- 4-[(4-Chlorophenyl)sulfanyl]-2,6-diphenylpyrimidine-5-carbonitrile (CAS 320418-44-8)
- (E)-{[4-(4-chlorophenyl)-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5-trien-3-yl]methylidene}amino cyclopropanecarboxylate (CAS 383147-87-3)
- (E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino N-(4-methylphenyl)carbamate (CAS 477872-48-3)
- 1-[(4-Chlorophenyl)sulfanyl]-4-[(2,3-dimethylphenoxy)methyl]-2-nitrobenzene (CAS 477869-52-6)
Recommended Standards
- 2-((4-Chlorobenzyl)amino)-4-(4-cyclohexylphenyl)-4-oxobutanoic acid (CAS 1024023-22-0)
- 5,6-Diiodoisobenzofuran-1,3-dione (CAS 25834-17-7)
- 5-Chloro-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)thiophene-2-carboxamide (CAS 302951-89-9)
- 6-((6-Chloro-2-methoxyacridin-9-yl)amino)-N,N-dimethylhexanamide (CAS 77420-95-2)
- N-(5-Oxopyrrolidin-3-yl)butyramide (CAS 958220-21-8)
- (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-methyl-3-(4-(trityloxy)phenyl)propanoic acid (CAS 1934266-53-1)
- Ethyl3-amino-5-bromo-pyridine-2-carboxylate (CAS 1334405-60-5)
- 7-Ethoxy-4-hydrazinylquinoline (CAS 767281-68-5)
- (3R,4R)-3-(Hydroxymethyl)hexahydropyridazin-4-ol (CAS 443649-13-6)
- Methyl 3-bromo-4-fluoro-5-hydroxybenzoate (CAS 1805552-09-3)
- 2-Chloro-4-methyl-6-(methylthio)pyrimidine (CAS 89466-59-1)
- 2-Nitro-4-aminodiphenylamine (CAS 2784-89-6)
- 2-[3-(3-fluorophenyl)oxetan-3-yl]ethyl 4-methylbenzenesulfonate (CAS 2543990-44-7)
- Semaglutide impurity 57 (CAS 2773558-06-6)
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