5-Hydroxythiophene-2-carbaldehyde CAS 144876-23-3

Purity 97%+In StockPharmaceutical Standards
CAS No.144876-23-3
Molecular FormulaC5H4O2S
Molecular Weight128.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Hydroxythiophene-2-carbaldehyde CAS 144876-23-3 chemical structure

Description

The occurrence of 5-Hydroxythiophene-2-carbaldehyde is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Hydroxythiophene-2-carbaldehyde (CAS 144876-23-3), molecular formula C5H4O2S and molecular weight 128.15 g/mol, is a CATO reference standard with documented purity and traceability.

5-Hydroxythiophene-2-carbaldehyde (C5H4O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Hydroxythiophene-2-carbaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H4O2S
Molecular Weight128.15 g/mol
Purity97%+
StorageStore at 2-8°C
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1998
Sulfur Atoms1

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