3-Hydroxythiophene-2-carboxamide CAS 57059-24-2

Purity 97%+In StockPharmaceutical Standards
CAS No.57059-24-2
Molecular FormulaC5H5NO2S
Molecular Weight143.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Hydroxythiophene-2-carboxamide CAS 57059-24-2 chemical structure

Description

The occurrence of 3-Hydroxythiophene-2-carboxamide is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-Hydroxythiophene-2-carboxamide (CAS 57059-24-2), molecular formula C5H5NO2S and molecular weight 143.16 g/mol, is a CATO reference standard with documented purity and traceability.

3-Hydroxythiophene-2-carboxamide (C5H5NO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Hydroxythiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H5NO2S
Molecular Weight143.16 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1973
Nitrogen Atoms1
Sulfur Atoms1

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