1-Methyl-1h-pyrazolo[4,3-b]pyridine-6-carboxylic acid CAS 1448852-25-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1448852-25-2
Molecular FormulaC8H7N3O2
Molecular Weight177.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Methyl-1h-pyrazolo[4,3-b]pyridine-6-carboxylic acid CAS 1448852-25-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Methyl-1h-pyrazolo[4,3-b]pyridine-6-carboxylic acid.

CATO supplies 1-Methyl-1h-pyrazolo[4,3-b]pyridine-6-carboxylic acid (CAS 1448852-25-2), a certified reference material (molecular formula C8H7N3O2, MW 177.16 g/mol) for analytical method development and quality control.

1-Methyl-1h-pyrazolo[4,3-b]pyridine-6-carboxylic acid (C8H7N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-Methyl-1h-pyrazolo[4,3-b]pyridine-6-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H7N3O2
Molecular Weight177.16 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Nitrogen Atoms3

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