2-Chloro-5-nitro-N-(4-(quinoxalin-2-yloxy)phenyl)benzamide CAS 647853-12-1
| CAS No. | 647853-12-1 |
| Molecular Formula | C21H13ClN4O4 |
| Molecular Weight | 420.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-Chloro-5-nitro-N-(4-(quinoxalin-2-yloxy)phenyl)benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-Chloro-5-nitro-N-(4-(quinoxalin-2-yloxy)phenyl)benzamide (CAS 647853-12-1) is a high-purity analytical reference standard with the molecular formula C21H13ClN4O4 and a molecular weight of 420.81 g/mol.
The molecular framework of 2-Chloro-5-nitro-N-(4-(quinoxalin-2-yloxy)phenyl)benzamide (C21H13ClN4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C21H13ClN4O4 |
| Molecular Weight | 420.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- (E)-4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)benzaldehyde O-(3-methoxybenzyl) oxime (CAS 1092343-78-6)
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- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenyl N-(4-methylphenyl)carbamate (CAS 339020-34-7)
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- 5-Chloro-N-methyl-6-oxo-N-phenyl-1-(3-(trifluoromethyl)benzyl)-1,6-dihydropyridine-3-carboxamide (CAS 400087-48-1)
- N-(3-chloro-2-methylphenyl)-4-((2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzamide (CAS 339025-34-2)
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Recommended Standards
- 2-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-oxo-N-[4-(trifluoromethyl)phenyl]acetamide (CAS 866152-59-2)
- 3-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzoic acid 4-chloro-phenyl ester (CAS 1311280-37-1)
- 4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzoic acid 4-chloro-phenyl ester (CAS 1311279-75-0)
- Opicapone Impurity 86 (CAS CATO-C4X-240486)
- 2-(4-(tert-Butoxycarbonyl)-2-oxo-3-phenylpiperazin-1-yl)acetic acid (CAS 1219625-14-5)
- 8DM1R7808M 5962-42-5 beta-Phosphonopropionic acid 3-Phosphonopropionic acid Propanoic acid, 3-phosphono- EINECS 227-738-8 UNII-8DM1R7808M (CAS 5962-42-5)
- (1-(4-Methoxyphenyl)-3-methyl-1H-pyrrol-2-yl)methanol (CAS 819081-92-0)
- (2E)-N-(3-Chloro-4-fluorophenyl)-3-[4-(2-methylpropyl)phenyl]prop-2-enamide (CAS 329777-61-9)
- 4,7-Dichloro-1-isoindolinone (CAS 954239-40-8)
- 4,4,4-Trifluoro-1-(2-fluorophenyl)butane-1,3-dione (CAS 111102-82-0)
- 5-Bromo-4-ethylthiazol-2-amine (CAS 1158211-11-0)
- 3-Chloro-6-(3,4-dimethoxyphenyl)pyridazine (CAS 132144-38-8)
- 2-(Cyclopropyl(1-(pyridin-2-yl)ethyl)amino)ethanol (CAS 1353986-19-2)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com