N-(Piperidin-4-yl)-6-(trifluoromethyl)pyrimidin-4-amine CAS 1448960-72-2
| CAS No. | 1448960-72-2 |
| Molecular Formula | C10H13F3N4 |
| Molecular Weight | 246.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 246.23 g/mol gives N-(Piperidin-4-yl)-6-(trifluoromethyl)pyrimidin-4-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(Piperidin-4-yl)-6-(trifluoromethyl)pyrimidin-4-amine (CAS 1448960-72-2), molecular formula C10H13F3N4 and molecular weight 246.23 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N-(Piperidin-4-yl)-6-(trifluoromethyl)pyrimidin-4-amine (C10H13F3N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 246.23 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H13F3N4 |
| Molecular Weight | 246.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- 2-(piperidin-4-yloxy)-6-(trifluoromethyl)pyridine (CAS 1428233-33-3)
- 2-(Piperidin-4-yloxy)-3-(trifluoromethyl)pyridine (CAS 1455156-01-0)
- 2-(Piperidin-4-yloxy)-5-(trifluoromethyl)pyridine (CAS 194668-48-9)
- n-(Piperidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine (CAS 874647-06-0)
- 4-(Piperidin-4-yl)furo[3,2-c]pyridine-2-carboxylic acid (CAS 1779130-90-3)
- 4-(Piperidin-4-yl)imidazo[1,5-a]pyrimidine-8-carboxylic acid (CAS 1263178-37-5)
- 6-(Piperidin-4-ylmethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 742051-67-8)
- [2-(4-Piperidin-1-yl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl]amine (CAS 1105196-28-8)
Recommended Standards
- 2,2,2-Trifluoro-1-(3-isobutoxyphenyl)ethanone (CAS 1443353-36-3)
- 2,2,2-Trifluoro-1-(4-methyl-3-propoxyphenyl)ethan-1-one (CAS 1443350-89-7)
- 4-(2,3-Dihydrobenzofuran-5-yl)-1,1,1-trifluorobutan-2-ol (CAS 1479669-58-3)
- 1-(4-Ethoxy-3,5-dimethylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1443349-44-7)
- 4-Chloro-2-ethynylphenol (CAS 1378976-47-6)
- 1-Benzyl-4-methylpyrrolidin-3-one (CAS 69079-25-0)
- N-[1-(1-benzofuran-2-yl)ethyl]-2-chloro-N-methylacetamide (CAS 1184567-77-8)
- Daprodustat Impurity 29 (CAS CATO-C4X-240729)
- 2-chloro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1382851-54-8)
- 3-Fluoro-N-(2-((6-(4-fluorophenyl)pyridazin-3-yl)oxy)ethyl)benzenesulfonamide (CAS 920256-46-8)
- 2-Amino-3-chlorobenzoic Acid (CAS 6388-47-2)
- 6-Bromo-2-fluoro-3-(trifluoromethoxy)benzaldehyde (CAS 524674-70-2)
- 1-(tert-butyldimethylsilyl)-5-chloro-1H-pyrrolo[2,3-b]pyridine (CAS 866546-08-9)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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