1-Hydroxy Alprazolam β-D-Glucuronide CAS 144964-58-9
| CAS No. | 144964-58-9 |
| Molecular Formula | C23H21ClN4O7 |
| Molecular Weight | 500.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-Hydroxy Alprazolam β-D-Glucuronide (CAS 144964-58-9), a certified reference material (molecular formula C23H21ClN4O7, MW 500.89 g/mol) for analytical method development and quality control.
1-Hydroxy Alprazolam β-D-Glucuronide (C23H21ClN4O7) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Hydroxy Alprazolam β-D-Glucuronide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H21ClN4O7 |
| Molecular Weight | 500.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
- N-(4-Bromo-2-methylphenyl)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 476484-61-4)
- N-Nitroso Flucloxacillin Impurity 22 (CAS CATO-C4X-164722)
- N-(2-Bromo-4-methylphenyl)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 476484-60-3)
- 3-O-tert-Butyldimethylsilyl Cholesterol (CAS 57711-50-9)
- Ethyl 6-amino-5-cyano-4-(4-methoxyphenyl)-2-methyl-4H-pyran-3-carboxylate (CAS 89809-76-7)
- Methyl2-c-(trifluoromethyl)-alpha-d-ribofuranoside (CAS 159944-99-7)
- cis-9:10-Epoxy-12-hydroxystearic acid methyl ester Mixture of isomers (CAS 30602-82-5)
- 2-(4-(Hydroxymethyl)piperidin-1-yl)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1252523-47-9)
- Ethanone, 1-(2,7-diazaspiro[3.5]non-7-yl)- (CAS 1147422-10-3)
- N-(5-Cyclopropyl-1H-pyrazol-3-yl)butyramide (CAS 714230-80-5)
- 2-(4-Cyclohexylthiazol-2-yl)acetic acid (CAS 898382-22-4)
- 2-(((6-Bromo-4-oxoquinazolin-3(4H)-yl)methyl)amino)-N-(o-tolylcarbamoyl)acetamide (CAS 86816-92-4)
- Methyltrioctylsilane (CAS 3510-72-3)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
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