2-(((6-Bromo-4-oxoquinazolin-3(4H)-yl)methyl)amino)-N-(o-tolylcarbamoyl)acetamide CAS 86816-92-4
| CAS No. | 86816-92-4 |
| Molecular Formula | C19H18BrN5O3 |
| Molecular Weight | 444.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(((6-Bromo-4-oxoquinazolin-3(4H)-yl)methyl)amino)-N-(o-tolylcarbamoyl)acetamide.
2-(((6-Bromo-4-oxoquinazolin-3(4H)-yl)methyl)amino)-N-(o-tolylcarbamoyl)acetamide (CAS 86816-92-4) is a high-purity analytical reference standard with the molecular formula C19H18BrN5O3 and a molecular weight of 444.28 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 2-(((6-Bromo-4-oxoquinazolin-3(4H)-yl)methyl)amino)-N-(o-tolylcarbamoyl)acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 444.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H18BrN5O3 |
| Molecular Weight | 444.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
- (E)-1-(3-(3,4-Bis(trifluoromethoxy)phenyl)acryloyl)quinazolin-4(1H)-one (CAS 1295538-24-7)
- Tepotinib impurity 11 (CAS CATO-C4X-337411)
- 3-(1-(3-(5-Bromopyrimidin-2-yl)benzyl)-6-oxo-1,6-dihydropyridazin-3-yl)benzonitrile (CAS 1103506-77-9)
- 2-((4-Allyl-5-(((4-iodophenyl)amino)methyl)-4H-1,2,4-triazol-3-yl)thio)acetohydrazide (CAS 1306738-91-9)
- 3-(oxolan-2-yl)pyrrolidine-2-carboxylic acid hydrochloride (CAS 1864014-80-1)
- (S)-N-(Piperidin-3-yl)pyridine-4-carboxamide dihydrochloride (CAS 1338222-53-9)
- 3-Chloro-5-mercaptobenzonitrile (CAS 895572-41-5)
- (8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)(phenyl)methanone (CAS 339100-00-4)
- Z-1,4-cis-acha-oh (CAS 75695-14-6)
- 4-Bromo-2-chloro-5-fluorobenzoylchloride (CAS 203302-93-6)
- (-)-Epicatechin-3'-O-glucuronide (CAS 603133-91-1)
- N-(5-Bromo-2-cyanophenyl)acetamide (CAS 1693858-01-3)
- (2R,3R,4R,5R)-5-(benzyloxymethyl)-4-[tert-butyl(dimethyl)silyl]oxy-2-(3-fluorophenyl)-3-methoxy-tetrahydrofuran-2-ol (CAS 1583260-04-1)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
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