2-[trans-4-[4-[2-[[4-(Trifluoromethoxy)benzyl]carbamoyl]imidazo[1,2-a]pyridin-6-yl]phenyl]cyclohexyl]acetic Acid CAS 1449779-49-0
| CAS No. | 1449779-49-0 |
| Molecular Formula | C30H28F3N3O4 |
| Molecular Weight | 551.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[trans-4-[4-[2-[[4-(Trifluoromethoxy)benzyl]carbamoyl]imidazo[1,2-a]pyridin-6-yl]phenyl]cyclohexyl]acetic Acid (CAS 1449779-49-0) is a high-purity analytical reference standard with the molecular formula C30H28F3N3O4 and a molecular weight of 551.56 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-[trans-4-[4-[2-[[4-(Trifluoromethoxy)benzyl]carbamoyl]imidazo[1,2-a]pyridin-6-yl]phenyl]cyclohexyl]acetic Acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 551.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C30H28F3N3O4 |
| Molecular Weight | 551.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related trans Standards
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Recommended Standards
- Sofosbuvir Impurity 10 (CAS 863329-63-9)
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- Ticagrelor Impurity 146 (CAS CATO-C4X-1093146)
- N-(Carboxymethyl)-N-(3-methoxyphenyl)glycine (CAS 30042-66-1)
- 5-CHloro-n-propylpyrimidin-2-amine (CAS 1538515-91-1)
- 4,6-Dichloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine (CAS 881902-80-3)
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- (S)-2,2,2-Trifluoro-1-(4-(trifluoromethyl)phenyl)ethanamine (CAS 785766-87-2)
- (2R,4R)-tert-Butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 141850-54-6)
- 2-Bromomethyl-6-fluoro-benzoic acid methyl ester (CAS 197516-58-8)
- Ethyl 3-(3-(tert-Butylthio)-5-methoxy-1H-indol-2-yl)-2,2-dimethylpropanoate (CAS 1431697-75-4)
- (R)-3-(3,5-Difluorophenyl)-3-(1-(methylsulfonyl)piperidin-4-yl)propanal (CAS 718610-25-4)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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