4-Bromo-2,5-bifluorophenylboronic acid pinacol ester CAS 1451391-15-3
| CAS No. | 1451391-15-3 |
| Molecular Formula | C12H14BBrF2O2 |
| Molecular Weight | 318.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Bromo-2,5-bifluorophenylboronic acid pinacol ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 4-Bromo-2,5-bifluorophenylboronic acid pinacol ester (CAS 1451391-15-3), a certified reference material (molecular formula C12H14BBrF2O2, MW 318.95 g/mol) for analytical method development and quality control.
4-Bromo-2,5-bifluorophenylboronic acid pinacol ester (C12H14BBrF2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H14BBrF2O2 |
| Molecular Weight | 318.95 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 2-(5-Bromo-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1073339-12-4)
- 2-(2-Bromo-3,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1256781-62-0)
- 2-Bromo-4,5-difluorophenylboronic acid pinacol ester (CAS 1595078-09-3)
- 2-(4-Bromo-3,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2264017-64-1)
- 3-Bromo-2,6-difluorophenylboronic acid pinacol ester (CAS 2121513-51-5)
- 4-Bromo-2,3-difluorophenylboronic acid pinacol ester (CAS 2121515-07-7)
- 8-Bromo-2,4-dichloropyrido[3',2':4,5]furo[3,2-d]pyrimidine (CAS 1268241-77-5)
- 5-Bromo-2-(3-bromopyridin-2-yl)-2H-1,2,3-triazol-4-amine (CAS 1708168-56-2)
Recommended Standards
- 2,4-Difluoro-5-bromophenylboronic acid piancol ester (CAS 1419602-18-8)
- 2-(2,6-Dibromo-4-formylphenoxy)acetonitrile (CAS 827591-22-0)
- 2-(4,5-Dibromofuran-2-yl)pyrimidin-5-amine (CAS 1249123-47-4)
- 2,4-Dibromo-6-(isoxazol-5-yl)phenol (CAS 288401-34-3)
- 1-(Adamantan-1-yl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 548748-67-0)
- 6-Chloro-5-cyclopropoxy-N-methylpyridin-2-amine (CAS 1243375-65-6)
- 2,2,2-trifluoro-1-(1H-indol-3-yl)ethan-1-ol (CAS 116757-85-8)
- 2-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2311855-02-2)
- (2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trien-1-yl Acetate (CAS 4128-17-0)
- Methyl 4-(4-nitrophenoxy)picolinate (CAS 1131604-72-2)
- 3-(5-Fluoro-2-methoxybenzyl)piperidine hydrochloride (CAS 1171433-31-0)
- 6-Chloro-2-(trifluoromethyl)pyridine-3-acetic acid (CAS 1227578-83-7)
- 2-[(2S)-7-Bromo-1,2,3,4-tetrahydroquinoxalin-2-yl]ethan-1-ol (CAS 1638604-46-2)
- Fas C- Terminal Tripeptide (CAS 189109-90-8)
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