6-Bromo-3-chloro-2-fluorophenylboronic acid pinacol ester CAS 1451391-14-2
| CAS No. | 1451391-14-2 |
| Molecular Formula | C12H14BBrClFO2 |
| Molecular Weight | 335.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Bromo-3-chloro-2-fluorophenylboronic acid pinacol ester.
CATO supplies 6-Bromo-3-chloro-2-fluorophenylboronic acid pinacol ester (CAS 1451391-14-2), a certified reference material (molecular formula C12H14BBrClFO2, MW 335.40 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system, 6-Bromo-3-chloro-2-fluorophenylboronic acid pinacol ester is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 335.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Bromo-3-chloro-2-fluorophenylboronic acid pinacol ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14BBrClFO2 |
| Molecular Weight | 335.40 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- 2-(4-Bromo-2-chloro-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1111096-22-0)
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Recommended Standards
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