4-Fluoro-3-(2-chloro-phenylcarbamoyl)phenylboronic acid CAS 1451393-31-9
| CAS No. | 1451393-31-9 |
| Molecular Formula | C13H10BClFNO3 |
| Molecular Weight | 293.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Fluoro-3-(2-chloro-phenylcarbamoyl)phenylboronic acid (C13H10BClFNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 4-Fluoro-3-(2-chloro-phenylcarbamoyl)phenylboronic acid (CAS 1451393-31-9), a certified reference material (molecular formula C13H10BClFNO3, MW 293.49 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H10BClFNO3 |
| Molecular Weight | 293.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- (4-Chloro-3-((4-fluorophenyl)carbamoyl)phenyl)boronic acid (CAS 1449145-23-6)
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- 6-Chloro-5-iodoindolin-2-one (CAS 1507976-00-2)
- 3-Methyl-6-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine (CAS 1350994-90-9)
- Benzyl 2-(benzyloxy)-2-methylpropanoate (CAS 347400-73-1)
- 5-Chloro-3-iodopyridin-2-yl trifluoromethanesulfonate (CAS 1261365-87-0)
- 2-Methylthieno[3,2-d]pyrimidin-4(3H)-one (CAS 18678-13-2)
- 5-(Benzyloxy)-1,3-dimethyl-1h-pyrazole-4-carbaldehyde (CAS 1174307-24-4)
- 6-Bromo-5,5-dimethylhex-1-ene (CAS 56068-49-6)
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- 1-Benzyl-3-(biphenyl-4-yl)thiourea (CAS 854644-24-9)
- 5-Methyl-1-(2-methylbenzyl)-3-nitro-1h-pyrazole (CAS 898053-51-5)
- 263251-78-1 NMG938VJ6T D-3 Tavilermide [USAN:INN] UNII-NMG938VJ6T MIM-D3 MIM-D 3 D 3 (peptide) Tavilermide (CAS 263251-78-1)
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