3-Bromo-5-(piperazin-1-yl)pyrazolo[1,5-a]pyrimidine CAS 1454558-22-5
| CAS No. | 1454558-22-5 |
| Molecular Formula | C10H12BrN5 |
| Molecular Weight | 282.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-Bromo-5-(piperazin-1-yl)pyrazolo[1,5-a]pyrimidine (CAS 1454558-22-5), a certified reference material (molecular formula C10H12BrN5, MW 282.14 g/mol) for analytical method development and quality control.
The molecular framework of 3-Bromo-5-(piperazin-1-yl)pyrazolo[1,5-a]pyrimidine (C10H12BrN5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 3-Bromo-5-(piperazin-1-yl)pyrazolo[1,5-a]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12BrN5 |
| Molecular Weight | 282.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
Related Bromo Standards
- 4-Bromo-1-(4-methoxyphenyl)-3-methyl-1H-pyrazol-5-amine (CAS 1020703-38-1)
- 3-(2-Bromo-5-methoxyphenyl)-1-methyl-1h-pyrazol-5-amine (CAS 1152666-22-2)
- 3-(3-Bromo-4-methoxyphenyl)-1-methyl-1h-pyrazol-5-amine (CAS 1182961-37-0)
- 1-(2-Bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-2,2-dimethylpropan-1-one (CAS 1184852-23-0)
- 4-Bromo-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-c]pyridine (CAS 1220165-73-0)
- N-(5-bromo-2-cyanopyridin-3-yl)pivalamide (CAS 1246088-44-7)
- 4-Bromo-1-(4-methoxybenzyl)-1H-pyrazol-5-amine (CAS 1249926-03-1)
- 5-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-b]pyridine (CAS 1256957-72-8)
Recommended Standards
- 3-Bromo-9-methoxy-5,6,7,8-tetrahydropyrazolo-[5,1-b]quinazoline (CAS 1429309-36-3)
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- 3-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-c]pyridine (CAS 1416713-95-5)
- 4'-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-[1,1'-biphenyl]-2-ol (CAS 1467061-56-8)
- 3-Chloro-5-(2-chlorophenyl)isothiazole-4-carboxylic acid (CAS 306935-52-4)
- 2-Cyclopentyl-N-(3-((4-(4-fluorophenyl)piperazin-1-yl)sulfonyl)propyl)acetamide (CAS 1049342-52-0)
- 3-O-Benzyl 15,16-Dehydro Estrone Monoethylene Ketal (CAS 534572-67-3)
- Bromocriptine Impurity 16 (CAS CATO-C4X-136116)
- 4-(Aminomethyl)-3-cyano-2-(difluoromethoxy)benzoic acid (CAS 1807022-43-0)
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- 4-propyl-1H-1,2,3-triazole-5-carboxylic acid (CAS 1250730-75-6)
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