(3R,5S,6R)-3-amino-6-methyl-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-2-one CAS 1456803-38-5
| CAS No. | 1456803-38-5 |
| Molecular Formula | C14H17F3N2O |
| Molecular Weight | 286.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3R,5S,6R)-3-amino-6-methyl-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-2-one (C14H17F3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies (3R,5S,6R)-3-amino-6-methyl-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-2-one (CAS 1456803-38-5), a certified reference material (molecular formula C14H17F3N2O, MW 286.29 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (3R,5S,6R)-3-amino-6-methyl-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H17F3N2O |
| Molecular Weight | 286.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 3-(1-(2-Methoxyethyl)-1H-imidazol-4-yl)imidazo[1,5-a]pyridine-1-carboxylic acid (CAS 1422066-27-0)
- 4,4'-((4H-1,2,4-Triazol-4-yl)azanediyl)dibenzonitrile (CAS 148868-92-2)
- 1-(2,5-Dimethoxyphenyl)-4-hydrazinyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1416348-51-0)
- 7-(Diethylamino)coumarin-3-carbonyl Azide (CAS 157673-16-0)
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- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (3-acetylthiophen-2-yl)boronate (CAS 2223033-77-8)
- 4-(Aminomethyl)-3-nitrobenzoic acid (CAS 2372-51-2)
- 4-(2-Pyridyl)phenol (CAS 51035-40-6)
- 3-phenyl-1,2,4-thiadiazole (CAS 50483-82-4)
- 1142205-26-2 9338AC C15H16N2O3S [{2-Oxo-2-[(2-thienylmethyl)amino]ethyl}(phenyl)-amino]acetic acid (CAS 1142205-26-2)
- N-(Prop-2-yn-1-yl)acrylamide (CAS 123523-58-0)
- 1-(4-Phenyl-1,3-thiazol-2-yl)-3-piperidinecarboxylic acid (CAS 927803-58-5)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
Why CATO?
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