Atogepant Impurity 35 CAS 1456803-47-6

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.1456803-47-6
Molecular FormulaC14H14F6N2O
Molecular Weight340.26 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Atogepant Impurity 35 CAS 1456803-47-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 340.26 g/mol gives Atogepant Impurity 35 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Atogepant Impurity 35 (CAS 1456803-47-6) is a certified pharmaceutical impurity reference standard with the molecular formula C14H14F6N2O and a molecular weight of 340.26 g/mol.

Structurally, Atogepant Impurity 35 (C14H14F6N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 340.26 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Atogepant Impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H14F6N2O
Molecular Weight340.26 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF-containing
Nitrogen Atoms2

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