2,3-Difluorophenylacetonitrile CAS 145689-34-5
| CAS No. | 145689-34-5 |
| Molecular Formula | C8H5F2N |
| Molecular Weight | 153.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,3-Difluorophenylacetonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,3-Difluorophenylacetonitrile (CAS 145689-34-5) is a high-purity analytical reference standard with the molecular formula C8H5F2N and a molecular weight of 153.13 g/mol.
2,3-Difluorophenylacetonitrile (C8H5F2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5F2N |
| Molecular Weight | 153.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenylacetonitrile Standards
Recommended Standards
- 2-(Trifluoromethyl)thiazole (CAS 1449334-50-2)
- (S)-2-Amino-4,4-difluoropentanoic acid (CAS 148043-97-4)
- 5-(Trifluoromethyl)-1,3-thiazole (CAS 1434141-77-1)
- (2,2-Difluoroethyl)alanine (CAS 1496517-59-9)
- N-Acetoxy-2-((5-chloroquinolin-8-yl)oxy)acetimidamide (CAS 88757-85-1)
- 6-Amino-1H-indazole-3-carbonitrile (CAS 1360956-47-3)
- (3-Bromo-2,5,6-trifluorophenyl)methanamine 2,2,2-trifluoroacetate (CAS 1956377-81-3)
- Palmitoylethanolamide-d (CAS 946524-34-1)
- 3-Bromo-2-oxo-1(2H)-pyrazineacetic Acid Ethyl Ester (CAS 267876-34-6)
- Calcitonin (eel) (CAS 57014-02-5（free base）)
- (S)-tert-Butyl (4-methyl-1-oxopentan-2-yl)carbamate (CAS 58521-45-2)
- Humic acids, potassium salts (CAS 68514-28-3)
- 6-(4-Fluorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 439107-62-7)
- 1-His-N-a-ethylidene Semaglutide (CAS CATO-C4X-2226252)
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