1-(3-Bromothiophene-2-carbonyl)piperidine-4-carboxylic acid CAS 1456977-99-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1456977-99-3
Molecular FormulaC11H12BrNO3S
Molecular Weight318.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(3-Bromothiophene-2-carbonyl)piperidine-4-carboxylic acid CAS 1456977-99-3 chemical structure

Description

CATO manufactures 1-(3-Bromothiophene-2-carbonyl)piperidine-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

1-(3-Bromothiophene-2-carbonyl)piperidine-4-carboxylic acid (CAS 1456977-99-3) is a high-purity analytical reference standard with the molecular formula C11H12BrNO3S and a molecular weight of 318.19 g/mol.

The molecular framework of 1-(3-Bromothiophene-2-carbonyl)piperidine-4-carboxylic acid (C11H12BrNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC11H12BrNO3S
Molecular Weight318.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentBr-containing
Nitrogen Atoms1
Sulfur Atoms1

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