4-Bromo-2-fluoro-1-(2,2,2-trifluoroethoxy)benzene CAS 145767-77-7
| CAS No. | 145767-77-7 |
| Molecular Formula | C8H5BrF4O |
| Molecular Weight | 273.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Bromo-2-fluoro-1-(2,2,2-trifluoroethoxy)benzene (CAS 145767-77-7), molecular formula C8H5BrF4O and molecular weight 273.02 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 4-Bromo-2-fluoro-1-(2,2,2-trifluoroethoxy)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 273.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-Bromo-2-fluoro-1-(2,2,2-trifluoroethoxy)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5BrF4O |
| Molecular Weight | 273.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-(2-Bromo-5-fluorophenyl)-2,2,2-trifluoroethan-1-ol (CAS 1033805-68-3)
- 4-Bromo-2-fluoro-alpha-(trifluoromethyl)benzyl Alcohol (CAS 1033805-88-7)
- 1-Bromo-2-fluoro-4-(2,2,2-trifluoroethoxy)benzene (CAS 1036724-63-6)
- 5-Bromo-2-fluoro-alpha-(trifluoromethyl)benzyl Alcohol (CAS 1039827-16-1)
- 1-(2-Bromo-4-fluorophenyl)-2,2,2-trifluoroethan-1-ol (CAS 1086599-53-2)
- 5-Bromo-1-fluoro-2-methoxy-3-(trifluoromethyl)benzene (CAS 1224604-21-0)
- (6-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)methanol (CAS 1352718-85-4)
- 4-Bromo-1-fluoro-2-(2,2,2-trifluoroethoxy)benzene (CAS 1492025-34-9)
Recommended Standards
- 1-(Bromomethyl)-4-fluoro-2-(trifluoromethoxy)benzene (CAS 1323966-22-8)
- 3-Bromo-4-fluoro-alpha-(trifluoromethyl)benzyl Alcohol (CAS 150698-79-6)
- 2-Fluoro-4-(trifluoromethoxy)benzyl bromide (CAS 1240257-47-9)
- 1-(3-Bromo-5-fluorophenyl)-2,2,2-trifluoroethan-1-ol (CAS 1613518-87-8)
- Gd Standard Solution (CAS 7440-54-2)
- 2-(2,5-Dioxo-2,5-dihydro-1h-pyrrol-1-yl)-2-phenylacetic acid (CAS 777917-71-2)
- (2,5-dioxopyrrolidin-1-yl)dimethylsulfonium chloride (CAS 39095-38-0)
- 5-((4-Chlorophenoxy)methyl)furan-2-carbohydrazide (CAS 364628-38-6)
- 1-(4-butoxyphenyl)ethanone (CAS 5736-89-0)
- 2-Amino-N-(2-chlorobenzyl)-N-cyclopropylacetamide (CAS 1181728-97-1)
- (S)-2-Amino-N-(3-bromobenzyl)-N-ethylpropanamide (CAS 1354018-11-3)
- 4-(Pyrimidin-2-ylthio)butan-1-amine (CAS 642092-89-5)
- N-[(1-methyl-1H-pyrazol-4-yl)methyl]-2-(trifluoromethyl)aniline (CAS 1006466-09-6)
- Peptide Impurity 06 (CAS CATO-CPTD788806)
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