Rel-2,6-difluoro-4-((1's,4'r)-4'-propyl-[1,1'-bi(cyclohexan)]-4-yl)phenol CAS 145767-70-0

Purity 97%+In StockPharmaceutical Standards
CAS No.145767-70-0
Molecular FormulaC21H30F2O
Molecular Weight336.46 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Rel-2,6-difluoro-4-((1's,4'r)-4'-propyl-[1,1'-bi(cyclohexan)]-4-yl)phenol CAS 145767-70-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 336.46 g/mol gives Rel-2,6-difluoro-4-((1's,4'r)-4'-propyl-[1,1'-bi(cyclohexan)]-4-yl)phenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Rel-2,6-difluoro-4-((1's,4'r)-4'-propyl-[1,1'-bi(cyclohexan)]-4-yl)phenol (CAS 145767-70-0), molecular formula C21H30F2O and molecular weight 336.46 g/mol, is a CATO reference standard with documented purity and traceability.

Rel-2,6-difluoro-4-((1's,4'r)-4'-propyl-[1,1'-bi(cyclohexan)]-4-yl)phenol (C21H30F2O) contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H30F2O
Molecular Weight336.46 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentF-containing

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