Methyl 3-amino-5,6-dichloro-2-pyrazinecarboxylate CAS 1458-18-0
| CAS No. | 1458-18-0 |
| Molecular Formula | C6H11Cl2N3O2 |
| Molecular Weight | 228.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 3-amino-5,6-dichloro-2-pyrazinecarboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 3-amino-5,6-dichloro-2-pyrazinecarboxylate (CAS 1458-18-0), molecular formula C6H11Cl2N3O2 and molecular weight 228.08 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 3-amino-5,6-dichloro-2-pyrazinecarboxylate (C6H11Cl2N3O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 3-amino-5,6-dichloro-2-pyrazinecarboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H11Cl2N3O2 |
| Molecular Weight | 228.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 5-Amino-3-(3,4-dichlorophenyl)-1H-pyrazole (CAS 208519-10-2)
- 1-(2-amino-5-bromophenyl)propan-1-one (CAS 124623-15-0)
- 2-Amino-4-bromo-N-methylbenzimidamide (CAS 1260752-02-0)
- 1-(4-Amino-2-bromophenyl)propan-1-one (CAS 1342425-18-6)
- 1-Amino-6-bromo-2,3-dihydro-1H-inden-5-ol (CAS 1373223-16-5)
- 2-Amino-1-(5-bromo-2-methylphenyl)ethan-1-one (CAS 1520522-03-5)
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Recommended Standards
- 1-(2,4-Dichlorophenyl)-1h-pyrazol-4-amine (CAS 14044-29-2)
- 2,3-Dichloro-5,7-dimethylpyrido[3,4-b]pyrazine (CAS 1592561-70-0)
- 5-Allyl-2,4-dichloro-5H-pyrrolo[3,2-d]pyrimidine (CAS 1375303-26-6)
- 1-[5-chloro-2-(chloromethyl)phenyl]-1H-1,2,4-triazole (CAS 1602769-76-5)
- 4-Chloro-3-methyl-5-(trifluoromethyl)-1H-pyrazole (CAS 235106-12-4)
- (2-Chloropyridin-3-yl)(4-(2-hydroxyethyl)piperazin-1-yl)methanone (CAS 444791-56-4)
- (3-(Isopropylcarbamoyl)-5-nitrophenyl)boronic acid (CAS 871332-83-1)
- (S)-2,2-dimethyl-1-(3-(trifluoromethyl)phenyl)propan-1-amine (CAS 1388100-37-5)
- Sacubitril impurity 54 (CAS 149709-63-7)
- Bis(4-iodophenyl)methanone (CAS 5630-56-8)
- N-Methyl-1-nitroacridin-9-amine (CAS 19395-61-0)
- 4-(Dimethylamino)-5-methylthieno[2,3-d]pyrimidine-6-carboxylic acid (CAS 1082147-20-3)
- Tert-butyl ((benzyloxy)carbonyl)-L-phenylalaninate (CAS 7670-20-4)
- His-Aib-Semaglutide (CAS CATO-C4X-2226220)
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