5,6-Bis((4-fluorophenyl)amino)isoindoline-1,3-dione CAS 145915-60-2
| CAS No. | 145915-60-2 |
| Molecular Formula | C20H13F2N3O2 |
| Molecular Weight | 365.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5,6-Bis((4-fluorophenyl)amino)isoindoline-1,3-dione.
CATO supplies 5,6-Bis((4-fluorophenyl)amino)isoindoline-1,3-dione (CAS 145915-60-2), a certified reference material (molecular formula C20H13F2N3O2, MW 365.33 g/mol) for analytical method development and quality control.
Structurally, 5,6-Bis((4-fluorophenyl)amino)isoindoline-1,3-dione (C20H13F2N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 365.33 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H13F2N3O2 |
| Molecular Weight | 365.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Bis Standards
- 1-(5-(3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl)pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid (CAS 1326856-71-6)
- 2-Benzyl-5-(1-(4-fluorophenyl)-5-(methoxymethyl)-1H-1,2,3-triazol-4-yl)-1,3,4-oxadiazole (CAS 1081131-10-3)
- 2-(4-Fluorophenyl)-5-(1,3,5-trimethyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 956439-72-8)
- Ethyl 4-(2-((2-fluorophenyl)sulfonyl)acetamido)benzoate (CAS 1325304-62-8)
- 3-((3-Fluorophenyl)amino)-2-(naphthalen-1-yl)-1H-inden-1-one (CAS 1024474-09-6)
- (4-(2-Fluorophenyl)piperazin-1-yl)(5-methyl-3-phenylisoxazol-4-yl)methanone (CAS 505088-33-5)
- Methyl 5-((4-fluorophenyl)sulfonamido)benzo[b]thiophene-2-carboxylate (CAS 478248-44-1)
- 2-(3-Fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl dihydrogen phosphate (CAS 1256037-60-1)
Recommended Standards
- Tetramethyl 1-methyl-3a,7a-dihydro-1H-indole-2,3,3a,4-tetracarboxylate (CAS 1444-11-7)
- (5E)-5-({2-[3-(trifluoromethyl)phenoxy]phenyl}methylidene)-1,3-thiazolidine-2,4-dione (CAS 917607-23-9)
- N-Acetyl-2-O-methyl-α-neuraminic Acid 9-Acetate (CAS 143791-32-6)
- (E)-1-(1-(4-methyl-6-(trifluoromethyl)pyrimidin-2-yl)-1H-1,2,3-triazol-4-yl)-3-(thiophen-2-yl)prop-2-en-1-one (CAS 861211-63-4)
- N-(2-Chloro-4,6-dimethylphenyl)-2-((4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618432-50-1)
- 4-((2-Chloropyrimidin-4-yl)amino)cyclohexan-1-ol (CAS 1248118-63-9)
- 1,1,3,4-Tetrachloro-1,2,2,3,4,4-hexafluorobutane (CAS 423-38-1)
- tert-Butyl 1-amino-3-azabicyclo[4.1.0]heptane-3-carboxylate (CAS 1250993-33-9)
- Methyl 2-acetamido-2-(dimethoxyphosphoryl)acetate (CAS 89524-99-2)
- Cyclopentadienyl(octylcyclopentadienyl)-iron (CAS 51889-44-2)
- 2-(Tetrahydro-2H-pyran-4-yl)thiazol-4-amine (CAS 420095-10-9)
- 2-(6-(Trifluoromethyl)pyridin-2-yl)acetonitrile (CAS 1000564-90-8)
- morpholine, 4-[1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropyl]- (CAS 1206594-08-2)
- Cyclopeptide-5 (CAS 197172-76-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com