2,2-Dimethyl-3-(4-(trifluoromethyl)phenyl)pyrrolidine CAS 1459150-46-9
| CAS No. | 1459150-46-9 |
| Molecular Formula | C13H16F3N |
| Molecular Weight | 243.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2,2-Dimethyl-3-(4-(trifluoromethyl)phenyl)pyrrolidine (CAS 1459150-46-9) is a high-purity analytical reference standard with the molecular formula C13H16F3N and a molecular weight of 243.27 g/mol.
The molecular framework of 2,2-Dimethyl-3-(4-(trifluoromethyl)phenyl)pyrrolidine (C13H16F3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2,2-Dimethyl-3-(4-(trifluoromethyl)phenyl)pyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H16F3N |
| Molecular Weight | 243.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Dimethyl Standards
- 2,2-Dimethyl-3-(3-(trifluoromethyl)phenyl)pyrrolidine (CAS 1270801-02-9)
- 3,5-dimethyl-1-{1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-1H-pyrazol-4-amine (CAS 1291526-14-1)
- Methyl 3,4-dimethyl-5-sulfamoylbenzoate (CAS 1340445-56-8)
- (3,4-Dimethyl-benzenesulfonylamino)-acetic acid (CAS 695209-86-0)
- 3,3-Dimethyl-1-(4-sulfamoylphenyl)urea (CAS 91328-92-6)
- 3,4-Dimethyl-5-(methylsulfamoyl)benzoic acid (CAS 851168-79-1)
- 3-((4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)methyl)benzonitrile (CAS 1016690-59-7)
- 5,6-Dimethyl-3-oxo-N-phenyl-2,3-dihydropyridazine-4-carboxamide (CAS 1209096-63-8)
Recommended Standards
- {1-[2-(Trifluoromethyl)benzyl]cyclobutyl}methanamine (CAS 1439900-15-8)
- 2-Methyl-2-(4-(trifluoromethyl)benzyl)pyrrolidine (CAS 1519659-34-7)
- (1-{[3-(Trifluoromethyl)phenyl]methyl}cyclobutyl)methanamine (CAS 1439900-12-5)
- 4-(4-(Trifluoromethyl)benzyl)piperidine (CAS 192990-03-7)
- 4-Amino-2-ethoxy-5-nitrobenzoic Acid (CAS 86718-18-5)
- 1218119-42-6 2-[(4-Bromo-1H-pyrazol-1-yl)methyl]-1,3-thiazolidine-4-carboxylic acid (CAS 1218119-42-6)
- (Z)-2-(Acetoxyimino)-2-(2-aminothiazol-4-yl)acetic acid (CAS 110130-88-6)
- 2-(2,6-Difluorophenyl)-2-fluoroacetic acid (CAS 915030-46-5)
- Trientine Impurity 4 (CAS 281676-73-1)
- (3R,4S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid (CAS 267230-44-4)
- 1-(Difluoromethoxy)-3-iodo-2-methylbenzene (CAS 1261825-62-0)
- 6-Amino-8-(aminomethyl)-1H-purin-2(3H)-one (CAS 953072-21-4)
- {pyrazolo[1,5-a]pyridin-7-yl}methanol (CAS 885275-64-9)
- Cholecystokinin, CCK Tetrapeptide (30-33) (CAS 35144-91-3)
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