1-Acetyl-5-bromo-1H-indazole-4-carbonitrile CAS 1459253-68-9
| CAS No. | 1459253-68-9 |
| Molecular Formula | C10H6BrN3O |
| Molecular Weight | 264.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Acetyl-5-bromo-1H-indazole-4-carbonitrile (CAS 1459253-68-9) is a high-purity analytical reference standard with the molecular formula C10H6BrN3O and a molecular weight of 264.08 g/mol.
The molecular framework of 1-Acetyl-5-bromo-1H-indazole-4-carbonitrile (C10H6BrN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Acetyl-5-bromo-1H-indazole-4-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6BrN3O |
| Molecular Weight | 264.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
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- 1-(4-Hydroxy-3,5-dimethylphenyl)-2-(4-methoxybenzenesulfinyl)ethan-1-one (CAS 339100-54-8)
- 4-Benzylamino-1-butanol (CAS 59578-63-1)
- 3-Methyl-2-oxovaleric acid-d8 (sodium) (CAS 1795037-03-4)
- 1-(4-Chlorobenzyl)-3-isothiocyanato-1H-pyrazole (CAS 588695-59-4)
- Cefcapene Impurity 39 (CAS CATO-C4X-182439)
- (2,4,5,7-Tetrahydropyrano[3,4-c]pyrazol-7-yl)methanol (CAS 1422344-20-4)
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- Argatroban Impurity 46 (CAS 57876-69-4)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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