3-(difluoromethyl)cyclobutan-1-one CAS 1461713-56-3

Description

Compared with other compounds in its class, the molecular weight of 120.10 g/mol gives 3-(difluoromethyl)cyclobutan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-(difluoromethyl)cyclobutan-1-one (CAS 1461713-56-3), molecular formula C5H6F2O and molecular weight 120.10 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-(difluoromethyl)cyclobutan-1-one (C5H6F2O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-(difluoromethyl)cyclobutan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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