(3S)-3-(Difluoromethyl)pyrrolidine CAS 1638784-47-0
| CAS No. | 1638784-47-0 |
| Molecular Formula | C5H9F2N |
| Molecular Weight | 121.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 121.13 g/mol gives (3S)-3-(Difluoromethyl)pyrrolidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(3S)-3-(Difluoromethyl)pyrrolidine (CAS 1638784-47-0), molecular formula C5H9F2N and molecular weight 121.13 g/mol, is a CATO reference standard with documented purity and traceability.
(3S)-3-(Difluoromethyl)pyrrolidine (C5H9F2N) contains fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H9F2N |
| Molecular Weight | 121.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- (2S)-2-(Difluoromethyl)pyrrolidine (CAS 1262236-69-0)
- (R)-2-(Difluoromethyl)pyrrolidine (CAS 1344581-87-8)
- 3-(Difluoromethyl)pyrrolidine (CAS 1376435-67-4)
- (3R)-3-(Difluoromethyl)pyrrolidine (CAS 1444103-50-7)
- [1-(difluoromethyl)cyclopropyl]methanamine hydrochloride (CAS 1785097-21-3)
- 3-(Difluoromethyl)-3-methylazetidine (CAS 1785430-26-3)
- 3-(Difluoromethyl)cyclobutanamine (CAS 1785626-63-2)
- 2-(Difluoromethyl)-2-methylcyclopropan-1-amine (CAS 2107431-02-5)
Recommended Standards
- (2,2-Difluorocyclobutyl)methanamine (CAS 1582718-52-2)
- (2R)-4,4-Difluoro-2-methylpyrrolidine (CAS 1670259-97-8)
- 3,3-Difluoro-4-methylpyrrolidine (CAS 1554367-59-7)
- (2S)-4,4-Difluoro-2-methylpyrrolidine (CAS 1670259-98-9)
- Bis(7-methyl-1-octyl) Phthalate-3,4,5,6-d4 (CAS CATO-CCHM702137)
- 2-Bromo-3-methoxybenzyl alcohol (CAS 199436-55-0)
- Dibutylamine 2,2,2-trifluoroacetate (CAS 334-41-8)
- 2,3-Dihydro-1H-perimidin-2-one (CAS 5157-11-9)
- (2,4-Dimethylphenyl)(piperidin-4-yl)methanone (CAS 1016717-36-4)
- 3-Methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-4-ol (CAS 1261464-05-4)
- 4-(2-Fluoroethyl)piperidin-4-yl 2,2,2-trifluoroacetate (CAS 2608050-07-1)
- 2-(Propan-2-yloxy)ethanethioamide (CAS 1016885-92-9)
- 5-Methoxy-2,3-dihydro-1-benzofuran-4-carbaldehyde (CAS 156297-81-3)
- Tau Peptide (306-317) trifluoroacetate salt (CAS 1003007-59-7)
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