Ketoprofen Impurity 63 CAS 146257-39-8
| CAS No. | 146257-39-8 |
| Molecular Formula | C11H11NO2 |
| Molecular Weight | 189.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ketoprofen Impurity 63 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Ketoprofen Impurity 63 (CAS 146257-39-8, C11H11NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ketoprofen Impurity 63 (C11H11NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ketoprofen Impurity 63 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H11NO2 |
| Molecular Weight | 189.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 1 |
Related Ketoprofen Standards
- Ketoprofen Impurity 36 (CAS 872091-00-4)
- Ketoprofen Impurity 38 (CAS 64379-72-2)
- Ketoprofen Impurity 44 (CAS 131019-17-5)
- Ketoprofen Impurity 45 (CAS 1272414-15-9)
- Ketoprofen Impurity 22 (CAS 42872-29-7)
- Ketoprofen Impurity 43 (CAS 34040-63-6)
- Ketoprofen EP Impurity C (CAS 68432-95-1)
- Ketoprofen Impurity 46 (CAS 713-36-0)
Recommended Standards
- Rebamipide Impurity 47 (CAS 855177-00-3)
- Atazanavir EP Impurity K (CAS 162537-11-3)
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- Nemonoxacin Impurity 9 (CAS CATO-C4X-31289)
- Cefoperazone Impurity 56 (CAS CATO-C4X-114956)
- Pitolisant impurity 5 (CAS CATO-C4X-25205)
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- 2-Amino-4,5-dimethylthiophene-3-carbonitrile (CAS 4651-94-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com