Lafutidine impurity 20 CAS 146270-00-0
| CAS No. | 146270-00-0 |
| Molecular Formula | C23H25N3O3 |
| Molecular Weight | 391.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Lafutidine impurity 20 (CAS 146270-00-0) is a certified pharmaceutical impurity reference standard with the molecular formula C23H25N3O3 and a molecular weight of 391.46 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Lafutidine impurity 20 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 391.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lafutidine impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H25N3O3 |
| Molecular Weight | 391.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 3 |
Related Lafutidine Standards
- Lafutidine impurity 18 (CAS 146269-98-9)
- Lafutidine impurity 23 (CAS CATO-C4X-147623)
- Lafutidine (CAS 118288-08-7)
- Lafutidine (E)-Isomer (CAS 206449-94-7)
- Lafutidine Impurity 5 (CAS 118288-14-5)
- Lafutidine Impurity 24 (CAS 146270-02-2)
- rac Lafutidine (CAS 206449-93-6)
- Lafutidine Impurity 2 (CAS 174583-84-7)
Recommended Standards
- Metaraminol Impurity 106 (CAS CATO-C4X-2252106)
- Phenylephrine Impurity 74 (CAS CATO-C4X-146774)
- Metaraminol Impurity 109 (CAS CATO-C4X-2252109)
- Galanthamine Impurity 46 (4aR,6S,8aS) (CAS CATO-C4X-143546)
- Nifuratel Impurity 15 (CAS 31805-83-1)
- Ketorolac impurity 65 (CAS CATO-C4X-166965)
- Flucloxacillin EP Impurity D (CAS 3919-74-2)
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