5-Nitrobenzo[c]isoxazole-3-carboxylic acid CAS 146426-39-3
| CAS No. | 146426-39-3 |
| Molecular Formula | C8H4N2O5 |
| Molecular Weight | 208.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-Nitrobenzo[c]isoxazole-3-carboxylic acid (CAS 146426-39-3), a certified reference material (molecular formula C8H4N2O5, MW 208.13 g/mol) for analytical method development and quality control.
Structurally, 5-Nitrobenzo[c]isoxazole-3-carboxylic acid (C8H4N2O5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 208.13 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4N2O5 |
| Molecular Weight | 208.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 2 |
Related Nitrobenzo Standards
- 5-Nitrobenzo[d]isoxazole-3-carboxylic acid (CAS 28691-51-2)
- 6-Nitrobenzo[c]isoxazole-3-carboxylic acid (CAS 6501-77-5)
- 6-Nitrobenzo[d]isoxazole-3-carboxylic acid (CAS 28691-50-1)
- 2-(5-Nitrobenzo[d]isoxazol-3-yl)ethanol (CAS 642087-62-5)
- 6-Nitrobenzo[d]thiazole-2-carbaldehyde (CAS 831-44-7)
- 2-Ethyl-5-nitrobenzo[d]thiazole (CAS 134477-11-5)
- 7-Nitrobenzo[b]thiophene-3-carbaldehyde (CAS 109771-38-2)
- 5-Nitrobenzo[b]thiophene-2-carbaldehyde (CAS 4688-16-8)
Recommended Standards
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- 1-(3-Methyl-4-nitrophenyl)piperazine (CAS 192441-84-2)
- 2-Amino-3-nitrobenzyl Alcohol (CAS 139743-08-1)
- n-(2-(Allylamino)-2-oxoethyl)-4-bromobenzamide (CAS 923198-21-4)
- 2-Allyl-1,4-dimethylbenzene (CAS 42918-26-3)
- 1-(2,4-Dichlorophenoxy)-3-(2-imino-3-(2-(piperidin-1-yl)ethyl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propan-2-ol hydrochloride (CAS 1049728-05-3)
- n-Methyl-2-(thiazol-2-yl)propan-2-amine (CAS 1250643-63-0)
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- Semaglutide impurity 81 (CAS CATO-C4X-222681)
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