Rosuvastatin Impurity 83 CAS 147118-36-3
| CAS No. | 147118-36-3 |
| Molecular Formula | C16H20FN3O3S |
| Molecular Weight | 353.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Rosuvastatin Impurity 83 (CAS 147118-36-3), a pharmacopoeial impurity reference standard (molecular formula C16H20FN3O3S, MW 353.41 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Rosuvastatin Impurity 83 (C16H20FN3O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Rosuvastatin Impurity 83 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H20FN3O3S |
| Molecular Weight | 353.41 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rosuvastatin Standards
- Rosuvastatin Impurity 93 (CAS CATO-C4X-116993)
- Rosuvastatin Impurity 94 (CAS CATO-C4X-116994)
- Rosuvastatin Impurity 170 (CAS CATO-C4X-1169170)
- Rosuvastatin Impurity 109 (CAS 799842-06-1)
- Rosuvastatin Impurity 153 (CAS CATO-C4X-1169153)
- Rosuvastatin Impurity 106 (CAS 147118-37-4)
- Rosuvastatin Impurity 227 (CAS CATO-C4X-1169227)
- Rosuvastatin Impurity 230 (CAS CATO-C4X-1169230)
Recommended Standards
- Ezetimibe Impurity 92 (CAS 2469633-86-9)
- Apixaban Impurity 25 (CAS CATO-C4X-108825)
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- Salbutamol Impurity 110 (CAS 345322-10-3)
- Neratinib Impurity 43 (CAS 1222172-49-7)
- Finerenone Impurity 186 (CAS CATO-C4X-2880186)
- Atracurium Impurity 9 (CAS CATO-C4X-18509)
- 3-Difluoromethoxy-2-methoxy-6-(trifluoromethyl)pyridine (CAS 1227605-22-2)
- tert-Butyl 4-(4-amino-2-cyanophenyl)piperazine-1-carboxylate (CAS 288251-85-4)
- Ethyl benzo[b]thiophene-5-carboxylate (CAS 132526-16-0)
- 2-(Piperidin-1-yl)acetaldehyde (CAS 4671-96-9)
- 2-Amino-5-fluoro-6-methylpyridine (CAS 110919-71-6)
- 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-4-(prop-2-en-1-yl)piperazine (CAS 865660-14-6)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com