6-Chloro-2-methylimidazo[1,2-b]pyridazine-3-carboxylic acid CAS 14714-22-8
| CAS No. | 14714-22-8 |
| Molecular Formula | C8H6ClN3O2 |
| Molecular Weight | 211.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Chloro-2-methylimidazo[1,2-b]pyridazine-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Chloro-2-methylimidazo[1,2-b]pyridazine-3-carboxylic acid (CAS 14714-22-8) is a high-purity analytical reference standard with the molecular formula C8H6ClN3O2 and a molecular weight of 211.61 g/mol.
6-Chloro-2-methylimidazo[1,2-b]pyridazine-3-carboxylic acid (C8H6ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6ClN3O2 |
| Molecular Weight | 211.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-Chloro-6-methyl-3-nitro-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-15-7)
- 3-Chloro-6-methyl-7-nitro-1H-indazole (CAS 1000342-46-0)
- 3-Chloro-6-methylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 1015846-76-0)
- Methyl 5-chloro-1H-imidazo[4,5-b]pyridine-2-carboxylate (CAS 1044772-73-7)
- Methyl 5-chloro-7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate (CAS 1095822-65-3)
- 5-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-carboxylic acid (CAS 1095822-69-7)
- 7-Chloro-5-methylimidazo[1,2-c]pyrimidine-2-carboxylic acid (CAS 117186-21-7)
- 6-Chloro-N'-hydroxy-1,3-benzoxazole-2-carboximidamide (CAS 1172606-71-1)
Recommended Standards
- 2-(Chloromethyl)-6-nitro-1H-benzo[d]imidazole (CAS 14625-39-9)
- 7-Chloro-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 1495016-23-3)
- 5-Chloro-1-methylpyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione (CAS 1447966-10-0)
- 7-Chloro-2-methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid (CAS 1496340-90-9)
- 4,7-Dibromo-1H-imidazo[4,5-c]pyridin-2(3H)-one (CAS 161836-10-8)
- tert-butyl 3-(2-oxopropyl)morpholine-4-carboxylate (CAS 1696474-78-8)
- 1-Bromo-3,5-dineopentylbenzene (CAS 120173-44-6)
- 1,3-Bis((R)-1-phenylpropyl)-1H-imidazol-3-iumchloride (CAS 2757082-92-9)
- 6,7-Difluoro-2-methyl-2,3-dihydrobenzofuran-3-amine (CAS 1342958-61-5)
- (3-Cyclopropoxy-5-ethylpyridin-4-yl)methanamine (CAS 1243439-53-3)
- 3-Amino-2-chloro-6-fluorobenzoic acid (CAS 1186194-01-3)
- 1-Benzyl-3-trifluoromethyl-piperazine (CAS 167566-34-9)
- (4-Dimethylamino)phenyl)diphenylphosphine oxide (CAS 797-72-8)
- D-Asp9-Tirzepatide (CAS CATO-CPTD788923)
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