Ethyl 6-chloro-2-methylimidazo[1,2-b]pyridazine-3-carboxylate CAS 14714-18-2
| CAS No. | 14714-18-2 |
| Molecular Formula | C10H10ClN3O2 |
| Molecular Weight | 239.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 6-chloro-2-methylimidazo[1,2-b]pyridazine-3-carboxylate (CAS 14714-18-2), molecular formula C10H10ClN3O2 and molecular weight 239.66 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 6-chloro-2-methylimidazo[1,2-b]pyridazine-3-carboxylate (C10H10ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 6-chloro-2-methylimidazo[1,2-b]pyridazine-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10ClN3O2 |
| Molecular Weight | 239.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- Ethyl 7-chloro-2-methyl-2H-pyrazolo[4,3-b]pyridine-6-carboxylate (CAS 100478-09-9)
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Recommended Standards
- Ethyl 4-chloro-6-methylpyrazolo[1,5-a]pyrazine-2-carboxylate, 97% (CAS 1449598-75-7)
- ETHYL 6-CHLOROOXOINDOLINE-3-CARBOXYLATE (CAS 14750-18-6)
- Ethyl 5-chloro-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 1431654-56-6)
- Ethyl 5-chloro-3-hydroxy-1H-indole-2-carboxylate (CAS 153501-18-9)
- 5-(2-Methylphenyl)-1,2,4-thiadiazol-3-amine (CAS 1086385-74-1)
- tert-Butyl 3-(hydroxymethyl)-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridine-5-carboxylate (CAS 1250998-91-4)
- 2-(5,6-Dimethyl-3-oxoisobenzofuran-1(3H)-ylidene)acetonitrile (CAS 58138-31-1)
- (Dimethylsulfamoyl)(2-hydroxyethyl)methylamine (CAS 1175697-76-3)
- 2-(Difluoromethyl)-5-fluoropyridine-4-carboxylic acid (CAS 1806756-70-6)
- Tert-butyl (S)-3-(cyclopropyl(hydroxy)methyl)azetidine-1-carboxylate (CAS 2350032-90-3)
- 2-Methyl-3-((5-nitropyridin-2-yl)oxy)pyridine (CAS 200940-26-7)
- 3-(((Benzyloxy)carbonyl)amino)propane-1-sulfonic acid (CAS 77693-74-4)
- Ethyl 2-(4-butylphenyl)cyclopropane-1-carboxylate (CAS 832737-95-8)
- Semaglutide impurity 50 (CAS 2773558-66-8)
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