6-Hydroxy-4-oxo-4h-chromene-2-carboxylic acid CAS 14718-40-2
| CAS No. | 14718-40-2 |
| Molecular Formula | C10H6O5 |
| Molecular Weight | 206.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Hydroxy-4-oxo-4h-chromene-2-carboxylic acid (CAS 14718-40-2), molecular formula C10H6O5 and molecular weight 206.15 g/mol, is a CATO reference standard with documented purity and traceability.
6-Hydroxy-4-oxo-4h-chromene-2-carboxylic acid (C10H6O5) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6O5 |
| Molecular Weight | 206.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Hydroxy Standards
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- 8-Hydroxy-4-oxo-4H-chromene-2-carboxylic acid (CAS 129472-71-5)
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Recommended Standards
- 1H-Indazole-3,7-dicarboxylic acid (CAS 1427504-82-2)
- 2-(5-Oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)benzoic acid (CAS 1501335-06-3)
- 5-(Furan-2-carbonyl)furan-2-carboxylic acid (CAS 1399657-85-2)
- 3-Nitro-2,4-quinolinediol (CAS 15151-57-2)
- N-(4-Bromo-3-methylphenyl)-4-(thiophen-2-yl)tetrahydro-2H-pyran-4-carboxamide (CAS 877651-29-1)
- 4-(4-Chlorophenyl)-2-phenyl-6-(phenylsulfanyl)pyrimidine-5-carbonitrile (CAS 320418-48-2)
- 3-((4-Fluorophenyl)ethynyl)aniline (CAS 138781-97-2)
- 5-Fluoro-7-phenyl-1,2,3,4-tetrahydroisoquinoline (CAS 2418540-66-4)
- 2-Formylquinoline 1-oxide (CAS 54618-45-0)
- (E)-1,3-Butadienyl Acetate (CAS 35694-20-3)
- N-(5-Amino-2-fluorophenyl)-4-fluorobenzamide (CAS 926214-61-1)
- 2-benzyl-5-methyloctahydropyrrolo[3,4-c]pyrrole (CAS 86755-80-8)
- 2-(2,6-Dichloropyridin-3-yl)-5-methyl-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431727-96-6)
- Liraglutide(3-31)TFA Salt (CAS CATO-C4X-19921)
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