1-(3-(Trifluoromethyl)phenyl)piperidin-4-one CAS 147378-74-3
| CAS No. | 147378-74-3 |
| Molecular Formula | C12H12F3NO |
| Molecular Weight | 243.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(3-(Trifluoromethyl)phenyl)piperidin-4-one is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 243.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
1-(3-(Trifluoromethyl)phenyl)piperidin-4-one (CAS 147378-74-3), molecular formula C12H12F3NO and molecular weight 243.22 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(3-(Trifluoromethyl)phenyl)piperidin-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12F3NO |
| Molecular Weight | 243.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 5-(Trifluoromethyl)-2H-spiro[benzofuran-3,3'-pyrrolidine] (CAS 1047657-74-8)
- 5-(2-(Trifluoromethyl)phenoxy)pentanenitrile (CAS 1303743-39-6)
- 5-(3-(Trifluoromethyl)phenoxy)pentanenitrile (CAS 1307520-98-4)
- 3-(4-(Trifluoromethyl)benzyl)pyrrolidin-2-one (CAS 1350989-17-1)
- 1-(4-(Trifluoromethyl)benzyl)pyrrolidin-2-one (CAS 1353087-69-0)
- 4-Methyl-4-(3-(trifluoromethyl)phenyl)pyrrolidin-2-one (CAS 1488856-28-5)
- 4-Methyl-4-(4-(trifluoromethyl)phenyl)pyrrolidin-2-one (CAS 1494528-00-5)
- 1-(2-(Trifluoromethyl)phenyl)piperidin-4-one (CAS 821792-43-2)
Recommended Standards
- Methyl 4-oxo-4,5-dihydroimidazo[1,2-a]quinoxaline-8-carboxylate (CAS 1452864-17-3)
- tert-Butyl (2-hydroxyethyl)(2,2,2-trifluoroethyl)carbamate (CAS 1488194-13-3)
- 6-(3,4,5-Trifluorophenoxy)hexanenitrile (CAS 1443354-23-1)
- 6-(2,3,4-Trifluorophenoxy)hexanenitrile (CAS 1443354-01-5)
- 2-(4-Methoxyphenyl)-2-(1-piperidyl)-acetic acid hydrochloride (CAS 1672675-18-1)
- (2E)-3-(4-tert-Butylphenyl)-1-(2-chlorophenyl)prop-2-en-1-one (CAS 1354942-09-8)
- tert-Butyl 4-(2-Ethoxy-2-oxoethyl)-5,5-difluoro-5,6-dihydropyridine-1(2H)-carboxylate (CAS 1823275-22-4)
- 4-(4-Bromo-3-methylphenyl)oxazolidin-2-one (CAS 1519517-20-4)
- (Z)-3-(3-Chlorobut-2-en-1-yl)-8-methoxy-2-methylquinolin-4(1H)-one (CAS 1164516-15-7)
- N'-(2-Hydroxybenzylidene)-5-(2-((4-methylbenzyl)oxy)phenyl)-1H-pyrazole-3-carbohydrazide (CAS 303106-50-5)
- (S)-3-AMINO-3-(3-NITRO-PHENYL)-PROPIONIC ACID (CAS 734529-57-8)
- 2-(Benzo[d]thiazol-2-yl)-1H-indene-1,3(2H)-dione (CAS 52625-67-9)
- Benzyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate (CAS 363186-06-5)
- Tirzepatide Impurity 16 (CAS CATO-C4X-324016)
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