Candesartan Cilexetil Impurity 37 CAS 147404-74-8
| CAS No. | 147404-74-8 |
| Molecular Formula | C22H19N3O5 |
| Molecular Weight | 405.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Candesartan Cilexetil Impurity 37.
As a process- or degradation-related impurity, Candesartan Cilexetil Impurity 37 (CAS 147404-74-8, C22H19N3O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Candesartan Cilexetil Impurity 37 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 405.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Candesartan Cilexetil Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H19N3O5 |
| Molecular Weight | 405.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 3 |
Related Candesartan Standards
- Candesartan impurity 4 (CAS CATO-C4X-15724)
- Candesartan Cilexetil Impurity 39 (CAS CATO-C4X-123439)
- Candesartan Cilexetil Impurity 24 (CAS 139481-28-0)
- Candesartan Cilexetil Impurity 38 (CAS CATO-C4X-123438)
- Candesartan Cilexetil Impurity 46 (CAS 1821386-35-9)
- Candesartan Ethyl Ester Desethyl Analog (CAS 1225044-20-1)
- Candesartan Cilexetil Impurity 20 (CAS CATO-C4X-123420)
- Candesartan Cilexetil EP Impurity G(Candesartan) (CAS 139481-59-7)
Recommended Standards
- Tadalafil EP Impurity I (CAS 2378614-29-8)
- 1-(Tert-butyl) 6',7'-dimethyl 4'-oxospiro[azetidine-3,2'-chromane]-1,6',7'-tricarboxylate (CAS 2961391-35-7)
- Tadalafil Impurity 173 (CAS CATO-C4X-1087173)
- Tadalafil Impurity N98 (CAS 1795790-92-9)
- Dapoxetine Impurity 4 (CAS 119357-34-5)
- Pramipexole impurity 75 (CAS CATO-C4X-110775)
- Budesonide EP Impurity G（monomer） (CAS CATO-C4X-138924)
- 8-Bromo-6-methylimidazo[1,2-a]pyridine hydrobromide (CAS 2060063-51-4)
- N-(6-Fluoro-8-phenyl-5,10-dihydroindeno[1,2-b]indol-2-yl)acetamide (CAS 920303-13-5)
- 3-(4-Chlorophenyl)-2h-1lambda6,2,6-thiadiazine-1,1-dione (CAS 1011398-17-6)
- N-Nitroso Nafamostat impurity 118 (CAS CATO-C4X-1332118)
- (R)-Imazamox (CAS 221298-64-2)
- 5-Chloro-6-methoxypicolinic acid (CAS 1214373-91-7)
- Acetyl Hexapeptide-38 (CAS 1400634-44-7)
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