2-(2,3,5,6-Tetrafluorophenoxy)acetic acid CAS 14742-39-3

Purity 97%+In StockPharmaceutical Standards
CAS No.14742-39-3
Molecular FormulaC8H4F4O3
Molecular Weight224.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2,3,5,6-Tetrafluorophenoxy)acetic acid CAS 14742-39-3 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

2-(2,3,5,6-Tetrafluorophenoxy)acetic acid (CAS 14742-39-3), molecular formula C8H4F4O3 and molecular weight 224.11 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(2,3,5,6-Tetrafluorophenoxy)acetic acid (C8H4F4O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC8H4F4O3
Molecular Weight224.11 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Halogen ContentF-containing

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Why CATO?