1-iodo-2-trimethylsilylacetylene CAS 18163-47-8
| CAS No. | 18163-47-8 |
| Molecular Formula | C5H9ISi |
| Molecular Weight | 224.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-iodo-2-trimethylsilylacetylene (CAS 18163-47-8) is a high-purity analytical reference standard with the molecular formula C5H9ISi and a molecular weight of 224.11 g/mol.
The molecular framework of 1-iodo-2-trimethylsilylacetylene (C5H9ISi) is characterized by iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 1-iodo-2-trimethylsilylacetylene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H9ISi |
| Molecular Weight | 224.11 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | I-containing |
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