Repaglinide Impurity 8 CAS 147770-08-9
| CAS No. | 147770-08-9 |
| Molecular Formula | C29H40N2O4 |
| Molecular Weight | 480.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Repaglinide Impurity 8 (CAS 147770-08-9), a pharmacopoeial impurity reference standard (molecular formula C29H40N2O4, MW 480.64 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Repaglinide Impurity 8 (C29H40N2O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Repaglinide Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H40N2O4 |
| Molecular Weight | 480.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 2 |
Related Repaglinide Standards
- Repaglinide EP Impurity D (CAS 147770-06-7)
- Repaglinide Impurity 25 (CAS CATO-C4X-118625)
- Repaglinide M2 Metabolite (2-Despiperidyl-2-(5-Carboxypentylamine Repaglinide)) (CAS 874908-12-0)
- Repaglinide USP Related Compound C (CAS 1803084-79-8)
- rac-Repaglinide USP Related Compound C (CAS 107362-12-9)
- Repaglinide M4 Metabolite (3'-Hydroxyl Repaglinide) (Mixture of Diastereomers) (CAS 874908-14-2)
- Repaglinide N-Oxide (CAS 121167-81-5)
- Repaglinide Methyl Ester (CAS 800365-89-3)
Recommended Standards
- Indacaterol Impurity 51 (CAS CATO-C4X-150051)
- Trimethyl(2,3,5,6-tetrafluoro-4-(triphenylsilyl)phenyl)silane (CAS 20083-06-1)
- Indocyanine Green Impurity 16 (CAS CATO-C4X-250316)
- Bis[bis(2-aminoethanethiolato)nickel]nickel dichloride (CAS 29993-19-9)
- Urapidil Impurity 21 (CAS CATO-C4X-192421)
- Apremilast Impurity 82 (CAS CATO-C4X-100982)
- Calcitriol impurity 41 (CAS CATO-C4X-151041)
- Almokalant Impurity 1 (CAS 123955-09-9)
- 6-Bromo-4-(difluoromethyl)picolinonitrile (CAS 1805221-58-2)
- 5-(4-Methylpiperazino)indan-1-one (CAS 866849-23-2)
- 4-Bromo-6-methoxy-2,3-dihydro-1H-indene (CAS 103038-40-0)
- Methyl 3,3,3-trifluoro-2-(trifluoromethyl)propanoate (CAS 360-54-3)
- 1-(Furan-2-ylmethyl)-3-(1-(3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)urea (CAS 1396865-01-2)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com