Apremilast Impurity 82 CAS CATO-C4X-100982
| CAS No. | CATO-C4X-100982 |
| Molecular Formula | C22H32N2O6S |
| Molecular Weight | 452.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Apremilast Impurity 82.
CATO supplies Apremilast Impurity 82 (CAS CATO-C4X-100982), a pharmacopoeial impurity reference standard (molecular formula C22H32N2O6S, MW 452.56 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C22H32N2O6S, Apremilast Impurity 82 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 452.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Apremilast Impurity 82 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H32N2O6S |
| Molecular Weight | 452.56 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast Impurity 78 (CAS CATO-C4X-100978)
- Apremilast Impurity 36 (CAS 253168-82-0)
- Apremilast Impurity 38 (CAS 2095036-40-9)
- Apremilast Impurity 52 (CAS CATO-C4X-100952)
- Apremilast impurity 15 (CAS 1384441-38-6)
- Apremilast Impurity 23 (CAS 2077897-94-8)
- Apremilast Impurity 45 (CAS CATO-C4X-100945)
- Apremilast Impurity 75 (CAS CATO-C4X-100975)
Recommended Standards
- 2-((4-Fluorobenzyl)thio)-3-(4-methoxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 477332-85-7)
- Avacopan Impurity 5 (CAS 1346623-09-3)
- 2-((3-Fluorobenzyl)thio)-3-(4-methoxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 477330-56-6)
- Dicyclohexyl(6,7,9,10-tetrahydrodibenzo[h,j][1,4,7]trioxacycloundecin-1-yl)phosphine (CAS 1256169-98-8)
- N-Methyl-N-(2-nitrobenzyl)cyclohexanamine hydrochloride (CAS 31611-42-4)
- Bisacodyl Impurity 6 (CAS 586-95-8)
- Terbutaline impurity 109 (CAS CATO-C4X-1183109)
- 5-Butyl-4-ethoxy-1-methylpyrimidin-2(1H)-one (CAS 145729-66-4)
- N-(3-Bromophenyl)-4-nitrobenzamide (CAS 99514-87-1)
- n-Methyladamantan-2-amine hydrochloride (CAS 10523-69-0)
- 2-(3-Fluoro-4-methoxyphenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane (CAS 2096995-36-5)
- 2-(2-Methylmorpholino)isonicotinic acid hydrochloride (CAS 1354958-10-3)
- 5-Chloro-3H-2-benzofuran-1-one (CAS 54109-03-4)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
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