2-(5-Methoxy-3-indolyl)-2-oxoacetic Acid CAS 14827-68-0
| CAS No. | 14827-68-0 |
| Molecular Formula | C13H13NO4 |
| Molecular Weight | 247.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(5-Methoxy-3-indolyl)-2-oxoacetic Acid (CAS 14827-68-0) is a high-purity analytical reference standard with the molecular formula C13H13NO4 and a molecular weight of 247.25 g/mol.
The molecular framework of 2-(5-Methoxy-3-indolyl)-2-oxoacetic Acid (C13H13NO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H13NO4 |
| Molecular Weight | 247.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 1 |
Related Methoxy Standards
- 4-(5-Methoxy-1H-indol-3-yl)-4-oxobutanoic acid (CAS 100394-00-1)
- 2-(6-Methoxy-2-methyl-4-oxoquinolin-1(4H)-yl)acetic acid (CAS 1083197-14-1)
- Methyl 2-(8-methoxy-4-oxoquinolin-1(4H)-yl)acetate (CAS 1170391-76-0)
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- 2-Methoxy-N-(4-methyl-3-(1h-tetrazol-1-yl)phenyl)acetamide (CAS 1209594-95-5)
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Recommended Standards
- Ethyl 2-(5-Methoxy-3-indolyl)-2-oxoacetate (CAS 14771-33-6)
- 5-Nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole (CAS 150187-64-7)
- 1-((Benzyloxy)carbonyl)-2,5-dihydro-1H-pyrrole-3-carboxylic acid (CAS 146309-25-3)
- Axitinib Impurity N26 (CAS 150187-67-0)
- (2R,3S,4S,5R)-2-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-carbonitrile hydrochloride (CAS 134665-72-8)
- 1,3-Dihydrobenzo[c]thiophene-5-carbaldehyde 2,2-dioxide (CAS 893566-63-7)
- 4-((4-Nitrobenzyl)oxy)benzaldehyde (CAS 67565-48-4)
- 1,1'-Carbonylbis(1,2,4-triazole) 1,1'-Carbonyldi(1,2,4-triazole) 41864-22-6 C2325 CDT (CAS 41864-22-6)
- 3-((2-Chloro-6-fluorobenzyl)thio)-4H-benzo[b][1,4]thiazine 1,1-dioxide (CAS 477868-97-6)
- Parisaponin I (CAS 561007-63-4)
- N-(tert-Butyl)-2,2-diphenylacetamide (CAS 36147-03-2)
- 1-(Trifluoroacetyl)-4-piperidinone (CAS 65220-86-2)
- 3,5-Dichloro-4-fluorocinnamic acid (CAS 1807432-86-5)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
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