2-(Trifluoromethyl)terephthalic acid CAS 1483-47-2
| CAS No. | 1483-47-2 |
| Molecular Formula | C9H5F3O4 |
| Molecular Weight | 234.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(Trifluoromethyl)terephthalic acid (C9H5F3O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(Trifluoromethyl)terephthalic acid (CAS 1483-47-2) is a high-purity analytical reference standard with the molecular formula C9H5F3O4 and a molecular weight of 234.13 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Trifluoromethyl)terephthalic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5F3O4 |
| Molecular Weight | 234.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- 5-(Trifluoromethyl)isophthalic acid (CAS 117186-03-5)
- 4-(Trifluoromethyl)benzo[d][1,3]dioxole-5-carboxylic acid (CAS 1784353-55-4)
- 4-(Trifluoromethyl)phthalic Acid (CAS 835-58-5)
- 1,5-Di(trifluoromethyl)-4-methylpent-3-en-2-one (CAS 885275-81-0)
- 1000566-45-9 2-(3-(TRIFLUOROMETHYL)-4-METHOXYPHENYL)ACETIC ACID 2-(4-METHOXY-3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID 4-Methoxy-3-(trifluoromethyl)phenylacetic acid AS06117 (CAS 1000566-45-9)
- 3-[3-(Trifluoromethyl)phenoxy]propanoic Acid (CAS 111140-93-3)
- 2-[2-(trifluoromethyl)phenoxy]propanoic acid (CAS 119411-77-7)
- 2-((3-(Trifluoromethyl)benzyl)oxy)acetic acid (CAS 868277-48-9)
Recommended Standards
- 2-Bromo-N-(3-methylcyclobutyl)butanamide (CAS 1403564-75-9)
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- 3-(1-methyl-1H-pyrrol-3-yl)propanoic acid (CAS 171858-12-1)
- 4-Bromo-2-methyloxazole (CAS 1240613-43-7)
- 2-(2-Aminobutan-2-yl)-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 1341412-63-2)
- Bromo-PEG3-azide (CAS 1446282-43-4)
- 2-Ethoxypyridin-4-ylboronic Acid (CAS 1072946-58-7)
- 2-Methoxy-3-(methylthio)benzaldehyde (CAS 1378737-56-4)
- 3-Ethoxy-N-ethylcyclobutan-1-amine (CAS 1525714-02-6)
- 3-Methyl-4-nitroacetanilide (CAS 51366-39-3)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com