5-(Methylamino)-2-phenyl-4-(4-(trifluoromethyl)phenyl)furan-3(2H)-one CAS 148681-61-2
| CAS No. | 148681-61-2 |
| Molecular Formula | C18H14F3NO2 |
| Molecular Weight | 333.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-(Methylamino)-2-phenyl-4-(4-(trifluoromethyl)phenyl)furan-3(2H)-one (CAS 148681-61-2), a certified reference material (molecular formula C18H14F3NO2, MW 333.30 g/mol) for analytical method development and quality control.
The molecular framework of 5-(Methylamino)-2-phenyl-4-(4-(trifluoromethyl)phenyl)furan-3(2H)-one (C18H14F3NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(Methylamino)-2-phenyl-4-(4-(trifluoromethyl)phenyl)furan-3(2H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14F3NO2 |
| Molecular Weight | 333.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 2-bromo-1-(3,5-ditert-butyl-4-hydroxy-phenyl)ethanone (CAS 14386-64-2)
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- Dimethyl 1-(2-(4-methoxyphenyl)-2-oxoethyl)-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 1350929-61-1)
- 2-tert-Butoxycarbonylamino-3-(4-trifluoromethyl-phenyl)-propionic acid (CAS 167496-29-9)
- n-Carbamoyl-2-(2-cyanophenoxy)propanamide (CAS 923243-64-5)
- 3-Hydroxy-6-methylpicolinamide (CAS 71322-16-2)
- 3-Fluoro-2,6-dimethoxybenzaldehyde (CAS 1286216-61-2)
- 2-(2-Methyl-4-oxo-1,4-dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-3-yl)ethyl cyclohexanecarboxylate (CAS 860611-06-9)
- 2-(azidomethyl)-2,3-dihydro-1H-isoindole-1,3-dione (CAS 26964-88-5)
- 4-Cyano-N-(2-methoxyphenyl)-3-methyl-5-(2-phenoxyacetamido)thiophene-2-carboxamide (CAS 503864-33-3)
- 3-(4-Fluorobenzo[d]isoxazol-3-yl)piperidine-2,6-dione (CAS 2623102-63-4)
- 2-(Pyridin-3-yl)-6-(trifluoromethyl)nicotinamide (CAS 1214335-39-3)
- 2,2-Dimethyl-3-(3-methylphenyl)pyrrolidine (CAS 1249187-89-0)
- [β-Asp]9-Semaglutide (CAS CATO-CPTD788605)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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