Aminomethylbenzoic Acid Impurity 1 CAS 14900-61-9
| CAS No. | 14900-61-9 |
| Molecular Formula | C16H15NO4 |
| Molecular Weight | 285.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Aminomethylbenzoic Acid Impurity 1 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Aminomethylbenzoic Acid Impurity 1 (CAS 14900-61-9) is a certified pharmaceutical impurity reference standard with the molecular formula C16H15NO4 and a molecular weight of 285.29 g/mol.
Based on its molecular formula C16H15NO4, Aminomethylbenzoic Acid Impurity 1 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 285.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H15NO4 |
| Molecular Weight | 285.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 1 |
Related Aminomethylbenzoic Standards
- Aminomethylbenzoic Acid Impurity 8 (CAS 1306130-66-4)
- Aminomethylbenzoic Acid Impurity 6 (CAS CATO-C4X-20936)
- Aminomethylbenzoic Acid Impurity 11 (CAS 1564748-46-4)
- Aminomethylbenzoic Acid Impurity 4 (CAS 165530-43-8)
- Aminomethylbenzoic Acid Impurity 3 (CAS 179076-85-8)
- Aminomethylbenzoic Acid Impurity 2 (CAS 98270-32-7)
- Aminomethylbenzoic Acid Impurity 4 HCl (CAS 549531-01-3)
- Aminomethylbenzoic Acid Impurity 5 HCl (CAS CATO-C4X-20935)
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- 4-Bromo-5-difluoromethoxy-2-fluorophenol (CAS 1804409-04-8)
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