Aminomethylbenzoic Acid Impurity 5 HCl CAS CATO-C4X-20935
| CAS No. | CATO-C4X-20935 |
| Molecular Formula | C16H16N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Aminomethylbenzoic Acid Impurity 5 HCl (CAS CATO-C4X-20935, C16H16N2O3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Aminomethylbenzoic Acid Impurity 5 HCl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 320.77 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H16N2O3 HCl |
| Molecular Weight | 320.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Aminomethylbenzoic Standards
- Aminomethylbenzoic Acid Impurity 8 (CAS 1306130-66-4)
- Aminomethylbenzoic Acid Impurity 1 (CAS 14900-61-9)
- Aminomethylbenzoic Acid Impurity 11 (CAS 1564748-46-4)
- Aminomethylbenzoic Acid Impurity 4 (CAS 165530-43-8)
- Aminomethylbenzoic Acid Impurity 3 (CAS 179076-85-8)
- Aminomethylbenzoic Acid Impurity 4 HCl (CAS 549531-01-3)
- Aminomethylbenzoic Acid Impurity 2 (CAS 98270-32-7)
- Aminomethylbenzoic Acid Impurity 6 (CAS CATO-C4X-20936)
Recommended Standards
- Osimertinib Impurity 17 (CAS CATO-C4X-204517)
- Valsartan Impurity 122 (CAS 1335138-31-2)
- Vardenafil Impurity 36 (CAS 224788-36-7)
- 2-Azetidinomethyl-3-chloro-4-fluorobenzophenone (CAS 898755-01-6)
- 4-Methyl-2-(1H-pyrrol-1-yl)-N-((1-(thiazol-2-yl)pyrrolidin-2-yl)methyl)thiazole-5-carboxamide (CAS 1790197-37-3)
- tert-Butyl 2-amino-3-cyano-6,6-dimethyl-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate (CAS 2407228-20-8)
- 2-(azetidin-3-yl)acetonitrile hydrochloride (CAS 1423057-36-6)
- Ethyl 2-(5-amino-1H-indol-1-yl)acetate hydrochloride (CAS 1221722-73-1)
- Coclaurine Impurity 111 (CAS 2158201-34-2(TFA Salt))
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
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