6-Chloro-2-(methoxymethyl)-N-methylpyrimidin-4-amine CAS 1490224-67-3
| CAS No. | 1490224-67-3 |
| Molecular Formula | C7H10ClN3O |
| Molecular Weight | 187.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Chloro-2-(methoxymethyl)-N-methylpyrimidin-4-amine is closely related to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Chloro-2-(methoxymethyl)-N-methylpyrimidin-4-amine (CAS 1490224-67-3), molecular formula C7H10ClN3O and molecular weight 187.63 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Chloro-2-(methoxymethyl)-N-methylpyrimidin-4-amine (C7H10ClN3O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-2-(methoxymethyl)-N-methylpyrimidin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H10ClN3O |
| Molecular Weight | 187.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-Chloro-3-ethynylquinoline (CAS 1000782-65-9)
- 2-Chloro-N-(1-ethyl-1h-pyrazol-4-yl)acetamide (CAS 1006432-63-8)
- 6-Chloro-N-(2-methoxyethyl)pyridazin-3-amine (CAS 1036569-59-1)
- 5-Chloro-6-(dimethylamino)-2-methylpyrimidin-4-ol (CAS 1135283-12-3)
- 1138220-54-8 3-[(6-Chloro-2-pyrazinyl)amino]-1-propanol (CAS 1138220-54-8)
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Recommended Standards
- (2-Chloro-4-(ethylamino)pyrimidin-5-yl)methanol (CAS 1428761-05-0)
- 5-Chloro-N-(2-methoxyethyl)pyrimidin-2-amine (CAS 1506399-39-8)
- (4-Chloro-6-(dimethylamino)pyrimidin-5-yl)methanol (CAS 1423029-78-0)
- 3-Chloro-6-ethynylisoquinoline (CAS 1578484-35-1)
- (1-Methyl-4-nitro-1H-pyrazol-3-yl)methanol (CAS 1201935-82-1)
- tert-Butyl 2-(3-bromophenoxy)acetate (CAS 277331-38-1)
- 1-(4-Chlorophenyl)-N-propylpropan-1-amine (CAS 1019371-52-8)
- 1-(3-Chlorophenyl)1,3-propanediol (CAS 51699-45-7)
- 2-(4-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetic acid (CAS 1200443-26-0)
- 4,5-Dimethyl-2-phenyl-1H-imidazol-1-yl acetate (CAS 802026-86-4)
- 5-Chloro-2-methoxy-3-(2-methoxyethoxy)pyridine (CAS 1820686-93-8)
- 2,3,4-Tribromothiophene (CAS 3141-25-1)
- Piperacillin Impurity 43 (CAS CATO-C4X-173243)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
Why CATO?
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