Tadalafil Impurity 39 CAS 14907-27-8
| CAS No. | 14907-27-8 |
| Molecular Formula | C12H14N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Tadalafil Impurity 39 (CAS 14907-27-8) is a certified pharmaceutical impurity reference standard with the molecular formula C12H14N2O2HCl and a molecular weight of 254.71 g/mol.
Based on its molecular formula C12H14N2O2HCl, Tadalafil Impurity 39 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 254.71 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14N2O2 HCl |
| Molecular Weight | 254.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tadalafil Standards
- Tadalafil Impurity 10 (CAS 100077-49-4)
- Tadalafil Impurity 75 (CAS 1093940-68-1)
- Tadalafil Impurity 76 (CAS 1093940-70-5)
- Tadalafil Impurity 99 (CAS 114152-23-7)
- Tadalafil Impurity 11 HCl (CAS 1190238-20-0)
- 【禁售不询】Tadalafil Impurity 43 (CAS 120-57-0)
- Tadalafil Impurity N1 (CAS 1220393-12-3)
- Tadalafil Impurity 119 (CAS 130812-44-1)
Recommended Standards
- Abemaciclib Impurity 70 (CAS 1231930-47-4)
- Solifenacin Impurity 13 (CAS 142999-60-8)
- Ceftizoxime Open-ring Dimer Impurity 55 (CAS CATO-C4X-179355)
- 4-Cycloheptylpiperidine (CAS 1493476-12-2)
- 4,4'-(Phenylmethylene)dianiline (CAS 603-40-7)
- tert-Butyl 4-oxa-1,9-diazaspiro[5.5]undecane-9-carboxylate (CAS 1160247-04-0)
- Ethyl 4-bromo-1-(2-chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazole-3-carboxylate (CAS 851728-84-2)
- 4-Bromo-1,1-difluorobutane (CAS 1457946-33-6)
- N-(3-(Benzyloxy)-5-(chloromethyl)phenyl)acetamide (CAS 1393577-01-9)
- Q-Peptide trifluoroacetate salt (CAS 1361235-89-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com