1-(3-Amino-3,4-dihydroquinolin-1(2h)-yl)-2,2,2-trifluoroethan-1-one CAS 1490799-90-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1490799-90-0
Molecular FormulaC11H11F3N2O
Molecular Weight244.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(3-Amino-3,4-dihydroquinolin-1(2h)-yl)-2,2,2-trifluoroethan-1-one CAS 1490799-90-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 244.21 g/mol gives 1-(3-Amino-3,4-dihydroquinolin-1(2h)-yl)-2,2,2-trifluoroethan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(3-Amino-3,4-dihydroquinolin-1(2h)-yl)-2,2,2-trifluoroethan-1-one (CAS 1490799-90-0), molecular formula C11H11F3N2O and molecular weight 244.21 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(3-Amino-3,4-dihydroquinolin-1(2h)-yl)-2,2,2-trifluoroethan-1-one (C11H11F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(3-Amino-3,4-dihydroquinolin-1(2h)-yl)-2,2,2-trifluoroethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H11F3N2O
Molecular Weight244.21 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF-containing
Nitrogen Atoms2

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