Valsartan Impurity 45 CAS 358685-13-9

Description

Compared with other compounds in its class, the molecular weight of 636.38 g/mol gives Valsartan Impurity 45 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

As a process- or degradation-related impurity, Valsartan Impurity 45 (CAS 358685-13-9, C33H24Br2N4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution, Valsartan Impurity 45 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 636.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Valsartan Impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Why CATO?

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